Associates with IL12B to form the IL23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity IL23 may constitute with IL17 an acute response to infection in peripheral tissues IL23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the JakStat signaling cascade, stimulates memory rather than naive TcellsIn addition to binding IL17E/IL25, IL17B R/IL17RB binds to IL17B but little is known about the composition of the receptor complex or the signaling pathways that it activates Similarly, the receptor for IL17D and the ligand for IL17RD/SEF are unknown, and the signaling pathways activated downstream of IL17C have not been characterizedJan 01, 03 · Recent discoveries of interleukin (IL)23, its receptor, and its signaltransduction pathway add to our understanding of cellular immunity IL23 is a heterodimer, comprising IL12 p40 and the recently cloned IL23specific p19 subunit
Hek Blue Il 23 Cells Il 23 Reporter Cells Invivogen